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Index > Protein center > GALC(Gene name) > Dog
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  • GALC (Gene name),
  • Galactocerebrosidase (Protein name ),  GALC_CANFA from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    GALC;
    Protein name:
    Galactocerebrosidase(GALCERase);
    Alternative:
    Galactosylceramidase;Galactocerebroside beta-galactosidase;Galactosylceramide beta-galactosidase;
    Organism:
    Dog (Canis familiarisCanis lupus familiaris). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon.
    Subcellular Location:
    Lysosome
    Protein Attributes:
    Sequence length:
    669
    Sequence:
    50:
    MTAAAGSAGH | AAVPLLLCAL | LVPGGAYVLD | DSDGLGREFD | GVGAVSGGGA | 
    100:
    TSRLLVNYPE | PYRSQILDYL | FKPNFGASLH | ILKVEIGGDG | QTTDGTEPSH | 
    150:
    MHYALDENFF | RGYEWWLMKE | AKKRNPNIIL | MGLPWSFPGW | IGKGFNWPYV | 
    200:
    NLQLTAYYIM | TWIVGAKHYH | DLDIDYIGIW | NERSFDINYI | KVLRRMLNYQ | 
    250:
    GLDRVKIIAS | DNLWEPISAS | MLLDSELLKV | IDVIGAHYPG | THTVKDAKLT | 
    300:
    KKKLWSSEDF | STLNSDVGAG | CLGRILNQNY | VNGYMTATIA | WNLVASYYEQ | 
    350:
    LPYGRCGLMT | AQEPWSGHYV | VESPIWVSAH | TTQFTQPGWY | YLKTVGHLEK | 
    400:
    GGSYVALTDG | LGNLTIIVET | MSHKQSACIR | PFLPYFNVSR | QFATFVLKGS | 
    450:
    FSEIPELQVW | YTKLGKPSER | YLFKQLDSLW | LLDSSSTFTL | ELQEDEIFTL | 
    500:
    TTLTVGSKGS | YPLPPKSEPF | PQIYEDDFDV | DYPFFSEAPN | FADQTGVFEY | 
    550:
    FTNIEDPGEH | RFTLRQVLNQ | RPITWAADAY | NTISIIGDYK | WSNLTVRCDV | 
    600:
    YIETPEKGGV | FIAGRVNKGG | ILIRSARGIF | FWIFANGTYR | VTGDLAGWVI | 
    650:
    YALGRVDVTA | KKWYTLTLII | KGRLSSGMLN | GKTVWKNIPV | SFPKNGWAAI | 
    669:
    GTHSFEFAQF | DNFHVEATR
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Dog GALCERase
    Cat.:
    E15006m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Dog GALCERase
    Cat.:
    E15006h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Dog GALCERase
    MSDS:
    Please sign in first.
    CLIA Kit for Dog GALCERase
    MSDS:
    Please sign in first.
    CLIA Kit for Dog GALCERase
    MSDS:
    Please sign in first.
    CLIA Kit for Dog GALCERase
    Cat.:
    U15006h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Dog GALCERase
    Polyclonal Antibody for Dog GALCERase
    Polyclonal Antibody for Dog GALCERase
    Monoclonal Antibody for Dog GALCERase
    Monoclonal Antibody for Dog GALCERase
    Monoclonal Antibody for Dog GALCERase
    Protein for Dog GALCERase
    Protein for Dog GALCERase
    Protein for Dog GALCERase

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning of the canine GALC cDNA and identification of the mutation causing globoid cell leukodystrophy in West Highland White and Cairn terriers."
      Victoria T. , Rafi M.A. , Wenger D.A.
      Genomics33:457-462(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;CATALYTIC ACTIVITY;ROLE IN DISEASE;VARIANTS GLD SER-158 AND SER-639
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