Protein name:
Galactocerebrosidase (GALCERase) ;
Alternative:
Galactosylceramidase ;Galactocerebroside beta-galactosidase ;Galactosylceramide beta-galactosidase ;
Organism:
Dog (Canis familiarisCanis lupus familiaris).
General Annotation
Function:
Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon.
Subcellular Location:
Lysosome
Protein Attributes:
50:
MTAAAGSAGH | AAVPLLLCAL | LVPGGAYVLD | DSDGLGREFD | GVGAVSGGGA |
100:
TSRLLVNYPE | PYRSQILDYL | FKPNFGASLH | ILKVEIGGDG | QTTDGTEPSH |
150:
MHYALDENFF | RGYEWWLMKE | AKKRNPNIIL | MGLPWSFPGW | IGKGFNWPYV |
200:
NLQLTAYYIM | TWIVGAKHYH | DLDIDYIGIW | NERSFDINYI | KVLRRMLNYQ |
250:
GLDRVKIIAS | DNLWEPISAS | MLLDSELLKV | IDVIGAHYPG | THTVKDAKLT |
300:
KKKLWSSEDF | STLNSDVGAG | CLGRILNQNY | VNGYMTATIA | WNLVASYYEQ |
350:
LPYGRCGLMT | AQEPWSGHYV | VESPIWVSAH | TTQFTQPGWY | YLKTVGHLEK |
400:
GGSYVALTDG | LGNLTIIVET | MSHKQSACIR | PFLPYFNVSR | QFATFVLKGS |
450:
FSEIPELQVW | YTKLGKPSER | YLFKQLDSLW | LLDSSSTFTL | ELQEDEIFTL |
500:
TTLTVGSKGS | YPLPPKSEPF | PQIYEDDFDV | DYPFFSEAPN | FADQTGVFEY |
550:
FTNIEDPGEH | RFTLRQVLNQ | RPITWAADAY | NTISIIGDYK | WSNLTVRCDV |
600:
YIETPEKGGV | FIAGRVNKGG | ILIRSARGIF | FWIFANGTYR | VTGDLAGWVI |
650:
YALGRVDVTA | KKWYTLTLII | KGRLSSGMLN | GKTVWKNIPV | SFPKNGWAAI |
669:
GTHSFEFAQF | DNFHVEATR
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Dog
ELISA Kit for Dog GALCERase
ELISA Kit for Dog GALCERase
ELISA Kit for Dog GALCERase
CLIA Kit for Dog GALCERase
CLIA Kit for Dog GALCERase
CLIA Kit for Dog GALCERase
Polyclonal Antibody for Dog GALCERase
Polyclonal Antibody for Dog GALCERase
Polyclonal Antibody for Dog GALCERase
Monoclonal Antibody for Dog GALCERase
Monoclonal Antibody for Dog GALCERase
Monoclonal Antibody for Dog GALCERase
Protein for Dog GALCERase
Protein for Dog GALCERase
Protein for Dog GALCERase
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;CATALYTIC ACTIVITY;ROLE IN DISEASE;VARIANTS GLD SER-158 AND SER-639